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Hallel Rosenberg-Fogler on Muck Rack

Hallel Rosenberg-Fogler

As seen in: BioRxiv
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Cancer-associated fibroblasts serve as decoys to suppress NK cell anti-cancer cytotoxicity

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By Aviad Ben-Shmuel, Yael Gruper, Oshrat Levi-Galibov, Hallel Rosenberg-Fogler
| BioRxiv
Abstract Cancer associated fibroblasts (CAFs) are among the most abundant components of the breast tumor microenvironment (TME) and major contributors to immune modulation. CAFs are well-known to regulate the activity of diverse types of immune cells including T cells, macrophages and dendritic cells, however little is known about their interaction with Natural killer (NK) cells, which constitute an important arm of anti-tumor immunity.
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