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As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.Articles
Direct effects of mast cell proteases, tryptase and chymase, on bronchial epithelial integrity proteins and anti-viral responses
Research article Open Access Published: 02 June 2021 BMC Immunology volume 22, Article number: 35 (2021) Cite this article 134 Accesses 1 Altmetric Metrics details Abstract Background Mast cells (MCs) are known to contribute to both acute and chronic inflammation. Bronchial epithelial cells are the first line of defence against pathogens and a deficient anti-viral response has been suggested to play a role in the pathogenesis of asthma exacerbations.
Azithromycin induces anti-viral effects in cultured bronchial epithelial cells from COPD patients
Mandy Menzel,1 Hamid Akbarshahi,1 Leif Bjermer,2 and Lena Ullera,1 Mandy Menzel 1Respiratory Immunopharmacology, Department of Experimental Medical Science, Lund University, Sweden Hamid Akbarshahi 1Respiratory Immunopharmacology, Department of Experimental Medical Science, Lund University, Sweden Leif Bjermer 2Lung medicine and Allergology, Department of Clinical Sciences, Lund University, Sweden Lena Uller 1Respiratory Immunopharmacology, Department of Experimental Medical Science, Lund...
Azithromycin induces anti-viral effects in cultured bronchial epithelial cells from COPD patients
Abstract Rhinovirus infection is a major cause of chronic obstructive pulmonary disease (COPD) exacerbations and may contribute to the development into severe stages of COPD. The macrolide antibiotic azithromycin may exert anti-viral actions and has been reported to reduce exacerbations in COPD. However, little is known about its anti-viral actions on bronchial epithelial cells at clinically relevant concentrations.
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