Hamidou Cisse

Abstract CIS43LS is a long-acting monoclonal antibody specific for the Plasmodium falciparum circumsporozoite protein expressed on sporozoites. We previously reported that CIS43LS is protective against P. falciparum infection as detected by thick blood smear (TBS; primary endpoint) in a phase 2 double-blind randomized trial involving 330 healthy Malian adults receiving placebo or a single intravenous infusion of 10 mg kg−1 or 40 mg kg−1 of CIS43LS (1:1:1).

Correction to: Nature Medicine https://doi.org/10.1038/s41591-020-1084-0, published online 26 October 2020. In the version of this article initially published, due to a formatting error in the data input files, the maximum likelihood estimation of parasite age presented was incorrect. In the third-to-last sentence of the “P.