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Han-ying Huang on Muck Rack

Han-ying Huang

As seen in: Nature, BioRxiv
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Articles

Availability of an inflammatory macrophage niche drives phenotypic and functional alterations in Kupffer cells

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By Lin Tian, Han-ying Huang, Yan-zhou Chen, Xin-nan Zheng
| BioRxiv
Abstract Inflammatory signals lead to recruitment of circulating monocytes and induce their differentiation into disease-associated macrophages. Therefore, whether blocking inflammatory monocytes can mitigate disease progression is being actively evaluated.
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A prognostic survival model based on metabolism-related gene expression in plasma cell myeloma

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By Juan Li, Han-ying Huang, Wei-da Wang, Huan-xin Lin
| Nature Verified
Abstract Accurate survival prediction of persons with plasma cell myeloma (PCM) is challenging. We interrogated clinical and laboratory co-variates and RNA matrices of 1040 subjects with PCM from public datasets in the Gene Expression Omnibus database in training (N = 1) and validation (N = 2) datasets. Genes regulating plasma cell metabolism correlated with survival were identified and seven used to build a metabolic risk score using Lasso Cox regression analyses.
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