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Hoxb4 upregulation by Xuan Bi Tong Yu Fang confers cardioprotection via repression of the Wnt/β-catenin pathway in myocardial ischemia-reperfusion injury
Abstract Background: Myocardial ischemia-reperfusion injury (MIRI) remains a significant challenge in treating cardiovascular diseases, contributing to substantial myocardial damage and a poor prognosis. Traditional Chinese medicine (TCM) offers promising alternatives, with Xuan Bi Tong Yu Fang (XBTYF) being a classical formula known for its protective effects. However, the therapeutic mechanisms of XBTYF in MIRI have not been fully explored.
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