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Hanee Lee

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Articles

Neuroprotective role of Hippo signaling by microtubule stability control in Caenorhabditis elegans

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By Hanee Lee, Junsu Kang, Sang-Hee Lee, Dowoon Lee
| eLife
eLife Assessment In their valuable study, Lee et al. explore a role for the Hippo signaling pathway, specifically wts-1/LATS and the downstream regulator yap, in age-dependent neurodegeneration and microtubule dynamics using C. elegans mechanosensory neurons as a model.
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Neuroprotective role of Hippo signaling by microtubule stability control in C. elegans

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By Hanee Lee, Junsu Kang, Sang-Hee Lee, Dowoon Lee
| BioRxiv
Abstract The evolutionarily conserved Hippo (Hpo) pathway has been shown to impact early development and tumorigenesis by governing cell proliferation and apoptosis. However, its post-developmental roles are relatively unexplored. Here, we demonstrate its roles in post-mitotic cells by showing that defective Hpo signaling accelerates age-associated structural and functional decline of neurons in C. elegans.
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Small Library for a Right to... by Hanee Lee

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By Hanee Lee
| generosity.com
Small Library for a Right to Imagine-Besi, Nepal
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