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Multi-Ancestry Genome-Wide Study Identifies Effector Genes and Druggable Pathways for Coronary Artery Calcification
Abstract Coronary artery calcification (CAC), a measure of subclinical atherosclerosis, predicts future symptomatic coronary artery disease (CAD). Identifying genetic risk factors for CAC may point to new therapeutic avenues for prevention. Currently, there are only four known risk loci for CAC identified from genome-wide association studies (GWAS) in the general population.
Neutrophil-to-Lymphocyte Ratio Associated with Adverse Events After Endovascular Aneurysm Repair (EVAR)
Highlights • Inflammation may be measured with the Neutrophil-to-Lymphocyte Ratio (NLR) • Pre-EVAR NLR may represent a patient's overall physiological state • Patient with NLR > 3.9 had worse reintervention and mortality rates • Results were significant even after controlling for age, diameter and comorbidities • Both short and long terms outcomes were associated with NLR Abstract Objective : The blood neutrophil-to-lymphocyte ratio (NLR) is a surrogate biomarker of systemic inflammation with...
A Centralized Vascular Access Service Team for Tunneled Catheter Placement Reduces Time-to-Insertion In A Large Academic Medical Center
Tunneled catheters (TCs) with and without subcutaneous ports are needed in patients who require prolonged vascular access. Delays in the placement of TCs can lead to increased lengths of stay and higher hospital costs. To increase placement of appropriate catheter type and decrease wait times, a centralized Vascular Access Service Team (VAST) was implemented at a large academic medical center. The objective of this review was to examine the efficiency of VAST.
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