Hannah Faisal Mubarak on Muck Rack

Hannah Faisal Mubarak

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Articles

Novel antibody language model accelerates IgG screening and design for broad-spectrum antiviral therapy

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By Hannah Faisal Mubarak, Wuwei Tan, Andrew Daniel Hoffmann, Yuanfei Sun
| biorxiv.org
Abstract Therapeutic antibodies have become one of the most influential therapeutics in modern medicine to fight against infectious pathogens, cancer, and many other diseases. However, experimental screening for highly efficacious targeting antibodies is labor-intensive and of high cost, which is exacerbated by evolving antigen targets under selective pressure such as fast-mutating viral variants.
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Physics-driven structural docking and protein language models accelerate antibody screening and design for broad-spectrum antiviral therapy

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By Wuwei Tan, Juncheng Wei, Hannah Faisal Mubarak, Andrew Daniel Hoffmann
| biorxiv.org
Abstract Therapeutic antibodies have become one of the most influential therapeutics in modern medicine to fight against infectious pathogens, cancer, and many other diseases. However, experimental screening for highly efficacious targeting antibodies is labor-intensive, which is exacerbated by evolving antigen targets under selective pressure such as fast-mutating viral variants.
Open in Who Shared Issue with article?
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