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Hannah Ruth Bridges

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Articles

Structure of the turnover-ready state of an ancestral respiratory complex I

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By Judy Hirst, Bozhidar Ivanov, Hannah Ruth Bridges, Owen David Jarman
| BioRxiv
Abstract Respiratory complex I is pivotal for cellular energy conversion, harnessing energy from NADH:ubiquinone oxidoreduction to drive protons across energy-transducing membranes for ATP synthesis. Despite detailed structural information on complex I, its mechanism of catalysis remains elusive due to lack of accompanying functional data for comprehensive structure-function analyses.
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