Hans Joerg Fehling

Research Article|Basic Annika C. Betzler, orcid.org/0000-0003-3261-7008 Ulm University Medical Center, Department of Oto-Rhino-Laryngology, Ulm, Germany Search for more papers by this author Katja Fiedler, Ulm University Medical Center, Department of Oto-Rhino-Laryngology, Ulm, Germany Ulm University, Department of Physiological Chemistry, Ulm, Germany Search for more papers by this author Thomas K.

Hideki Sanjo, Jun Nakayama, Takahiro Yoshizawa, Hans Joerg Fehling, Shizuo Akira and Shinsuke Taki J Immunol August 15, 2019, 203 (4) 783-788; DOI: https://doi.org/10.4049/jimmunol.1900202 Key Points TAK1 protects macrophages from proinflammatory cell death in TLR and TNFRI signaling. The cell death machinery is dependent on active caspases and GSDMD processing. TAK1 in macrophages both positively and negatively controls host inflammatory responses.

Hideki Sanjo, Jun Nakayama, Takahiro Yoshizawa, Hans Joerg Fehling, Shizuo Akira and Shinsuke Taki J Immunol June 26, 2019, ji1900202; DOI: https://doi.org/10.4049/jimmunol.1900202 Key Points TAK1 protects macrophages from proinflammatory cell death in TLR and TNFRI signaling. The cell death machinery is dependent on active caspases and GSDMD processing. TAK1 in macrophages both positively and negatively controls host inflammatory responses.