Haobo Yin

Abstract Digital product and service innovation (DPSI) has garnered significant interest from both management academics and practitioners. Prior research has established that information technology and digitization capabilities positively affect DPSI performance. The issue of whether and how digital orientation (DO) can enhance DPSI performance remains unanswered in digital healthcare.

Abstract Introduction Gastrointestinal (GI) cancers remain a major global health burden, with high incidence and mortality despite advances in multimodal therapies. Tertiary lymphoid structures (TLSs), ectopic lymphoid aggregates within the tumour microenvironment (TME), have emerged as key regulators of antitumour immunity and potential predictors of immunotherapy response. However, a focused synthesis of TLS biology specific to GI malignancies is still lacking.

Abstract While the segmentation of anatomical structures and pathological regions is indispensable for reliable disease assessment, contemporary algorithms often fail to achieve sharp demarcation. This deficiency stems from the high degree of morphological heterogeneity across different cases, which results in obscured contours and compromised segmentation accuracy.