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Haoxuan Ying

As seen in: Nature, MDPI, BioRxiv
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Articles

KDM4B/DHX9 promotes chemoresistance in small-cell lung cancer through the MYCN -driven signaling pathway

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By Qiong Lyu, Huiying Liu, Weitao Shen, Zhihong Lin, Yueming Zhang, Haoxuan Ying, Xiang Cao, Jian Zhang, Jian Shi, Zhengang Qiu, Qianshan Long
| Nature Verified
Abstract Small cell lung cancer (SCLC) is prone to developing chemoresistance, which is associated with epigenetic reprogramming. While LSD1-mediated histone demethylation has been reported, a systematic investigation into the role of histone demethylases in SCLC chemoresistance is lacking.
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Finding Your Voice: Using Generative AI to Help International Students Improve Their Writing

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By Leon Sterling, Chunchun Ye, Haoxuan Ying, Zhe Chen
| MDPI
1. Introduction Gen-AI tools built on large language models (LLMs), led by ChatGPT, have rapidly emerged over the last couple of years [1]. These tools present both opportunities and challenges for the entire academic community, including students and teachers. For students, the main opportunities are improving their ability to write reports of high quality, and becoming more efficient when undertaking writing tasks.
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SPP1+ tumor-associated macrophages induce radioresistance of nasopharyngeal carcinoma through crosstalk with the tumor microenvironment

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By Wenda Zhang, Lili Lin, Nan Li, Haoxuan Ying
| BioRxiv
Abstract The function and phenotype of tumor-associated macrophages (TAMs) influence the efficacy of radiotherapy. However, the effect of different subsets of TAMs on the radioresistance in nasopharyngeal carcinoma (NPC) still needs to be further explored. This study utilized single-cell RNA sequencing (scRNA-seq) to analyze 120,579 cells obtained from 15 NPC samples.
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