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Hartwig Roman Siebner on Muck Rack

Hartwig Roman Siebner

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As seen in: Nature, Wiley Online Library, BMJ Open, Frontiers, BioRxiv, Neurology, JNeurosci, Physician's Weekly
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Articles

Pharmacological targeting of dopamine D1 or D2 receptors evokes a rapid‐onset parkinsonian motor phenotype in mice

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By Hvidovre Denmark, Hartwig Roman Siebner, Mattias Rickhag, Mihai Atudorei
| Wiley Online Library Verified
ANOVA Analysis of Variance BAC Bacterial Artificial Chromosome Cre Cre recombinase D1R/D2R Dopamine D1/D2 receptor dSPNs/iSPNs Direct/indirect spiny projection neurons GABA Gamma Aminobutyric acid GENSAT Gene Expression Nervous System Atlas L-DOPA Levodopa/l-3,4-dihydroxyphenylalanine MAO-B Monoamine oxidase B PD Parkinson's disease SEM Standard error of the mean TOI Time of interest WT Wild-type 6-OHDA 6-hydroxydopamine 1 INTRODUCTION Parkinson's disease (PD) is a common, progressive motor...
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Single and paired TMS pulses engage spatially distinct corticomotor representations in human pericentral cortex

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By Lasse E. Christiansen, Chloe Chung, Hartwig Roman Siebner, Morten G. Jonsson
| BioRxiv
Abstract Single-pulse transcranial magnetic stimulation (TMS) of the primary motor hand area (M1-HAND) can assess corticomotor function in humans by evoking motor evoked potentials (MEP). Paired-pulse TMS at peri-threshold intensity elicits short-latency intracortical facilitation (SICF) with early peaks at inter-pulse intervals of 1.0-1.8ms (SICF1) and 2.4-3ms (SICF2).
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Mapping axon diameters and conduction velocity in the rat brain - different methods tell different stories of the structure-function relationship

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By Christian Stald Skoven, Mariam Andersson, Marco Pizzolato, Hartwig Roman Siebner
| BioRxiv
Abstract The structure-function relationship of nerve fibers describes an empirically determined linear relationship between axon diameter, myelin thickness (i.e., g-ratio), and conduction velocity. We investigated the structure-function relationship with different modalities in axons projecting through the corpus callosum of the rodent brain.
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