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Haser Sutcu

As seen in: Nature, BioRxiv
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Articles

The DNA damage response in myogenic C2C7 cells depends on the characteristics of ionizing particles

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By Haser Sutcu, Arthur Thomas-Joyeux, Mikael Cardot-Martin, Delphine Dugue
| BioRxiv
Abstract DNA integrity and stability are vital for proper cellular activity. Nevertheless, to treat cancer patients, DNA is the main target for inducing tumoral cell death. Nowadays, cancer treatment is improving by the development of new technologies, protocols and strategies. Amongst them, the charged particle radiotherapies are becoming prevalent. However, tumor-neighboring healthy tissues are still exposed to ionizing radiations (IR) and subject to late side effects.
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The DNA damage response relies on the characteristics of ionizing particles in myogenic cells

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By Haser Sutcu, François Vianna, Arthur Thomas-Joyeux, Mikael Cardot-Martins
| BioRxiv
Abstract DNA integrity and stability are vital for proper cellular activity. Nevertheless, to treat cancer patients, DNA is the main target for inducing tumoral cell death. Nowadays, cancer treatment is improving by the development of new technologies, protocols and strategies. Amongst them, the introduction of charged particles as a form of radiotherapy is underway. However, tumor-neighboring healthy tissues are still exposed to ionizing radiations (IR) and subject to late side effects.
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DNA-PKcs regulates myogenesis in an Akt-dependent manner independent of induced DNA damage - Cell Death & Differentiation

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By Haser Sutcu, Miria Ricchetti
| Nature Verified
Author notes Haser Hasan Sutcu Present address: Institut de Radioprotection et de Sûrété Nucléaire (IRSN), Radiobiology of Accidental Exposure Laboratory (PSE-SANTE/SERAMED/LRAcc), B.P. 17, 92262 Fontenay-aux-Roses, Cedex, France Authors and Affiliations Institut Pasteur, Team Stability of Nuclear & Mitochondrial DNA, Department of Developmental and Stem Cell Biology, CNRS UMR3738, 75015, Paris, France Haser Hasan Sutcu, Benjamin Montagne & Miria Ricchetti Université Pierre et Marie Curie...
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