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Hayuningbudi Saraswati on Muck Rack

Hayuningbudi Saraswati

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Articles

Discovery and Development of a Potent LIMK2 Isoform-Specific Degrader Click to copy article link Article link copied!

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By Thorsten Mosler, Thomas Hanke Verified, Hayuningbudi Saraswati
| dx.doi.org
Introduction Click to copy section linkSection link copied! The LIM kinases (LIMKs), LIMK1 and LIMK2, are dual-specific serine/threonine kinases. Each of these key signaling enzymes contain two LIM domains and a PDZ domain at their N-termini, followed by proline/serine-rich regions and a C-terminal kinase domain.
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