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Hazel Dunbar on Muck Rack

Hazel Dunbar

As seen in: Wiley Online Library, Thorax, RTÉ, Border Telegraph, Peeblesshire News
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Articles

The VEGF‐Mediated Cytoprotective Ability of MIF‐Licensed Mesenchymal Stromal Cells in House Dust Mite‐Induced Epithelial Damage

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By Hazel Dunbar, Co. Kildare Ireland, Ian Hawthorne, Courteney Tunstead
| Wiley Online Library Verified
1 Introduction Mesenchymal stromal cells (MSCs) are renowned for their cytoprotective abilities elicited through secreted factors including miRNA [1], mitochondrial DNA [2-4], lipids (prostaglandin E2), extracellular vesicles (EV) [5-7], metabolites (kynurenine) and cytokines (TNF and IL-6) [8-10]. Furthermore, newly emerging data outlines the importance of MSC-derived apoptotic bodies in their therapeutic efficacy, making the secretome their main mechanism of action [11-15].
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MAC attack: MSCs and macrophages join forces against chronic lung infection

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By Hazel Dunbar, Ian Hawthorne, Karen English Verified
| Thorax Verified
Macrophage Biology Bacterial Infection Respiratory Infection Systemic disease and lungs Mesenchymal stromal cells (MSCs) possess several characteristics that make them attractive as a potential adjunct therapy for acute and chronic infectious diseases.
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The ongoing search for a cure for asthma

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By Hazel Dunbar
| RTÉ Verified
Updated / Thursday, 12 Mar 2020 17:01 "First line treatment for asthma involves the use of an inhaler to deliver steroids, known as corticosteroids, to the lungs" Analysis: ongoing research is looking at how cells in lungs respond and communicate when they meet an asthmatic trigger Ireland currently has the fourth highest prevalence of asthma in the world which costs the Irish state €472 million per annum.
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