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Huntington’s disease is a rare neurodegenerative brain disease that is like having ALS, Parkinson’s and Alzheimer’s all at the same time. There is no cure, no treatment. Some of the symptoms of HD can be treated, but eventually a Huntington’s patient will be basically trapped inside their own bodies, relying on the care of others.
Heather Thurgood Wilmoth Heather Thurgood Wilmoth is a wife, mom, and caregiver for her husband, Nathan, who has Huntington’s disease (HD). Heather works for SuperTalk Mississippi Media, where she’s had a 30-plus year career in radio. She and Nathan have given talks about their experiences with HD for various organizations to spread awareness and use their social media platforms to educate about HD.
Hypofunction of the N-methyl–d-aspartate (NMDA) receptor is thought to exacerbate psychosis in patients diagnosed with schizophrenia. Consistent with this hypothesis, D-alanine, a co-agonist at the glycine site of the NMDA receptor, was shown to improve positive and cognitive symptoms when used as add-on therapy for schizophrenia treatment. However, D-alanine had to be administered at high doses (~7 g) to observe clinical effects.
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