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Heein Song on Muck Rack

Heein Song

As seen in: Stem Cell Reports
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Articles

APOL1 risk variants induce metabolic reprogramming of podocytes in patient-derived kidney organoids

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By Sébastien Dumas, Gangqi Wang, Lijun Ma, Franca M.R. Witjas, M. Cristina Avramut, Michael V. Rocco, Barry I. Freedman, Ton J Rabelink, Heein Song, H. Siebe Spijker
| Stem Cell Reports Verified
Keywords APOL1 kidney organoids stem cells mitochondria podocyte Introduction The incidence rate of end-stage kidney disease (ESKD) is disproportionately high in African Americans. Their susceptibility is largely explained by genetic variation in the gene encoding apolipoprotein L1 (APOL1) (Genovese et al., 2010; Parsa et al., 2013). APOL1 protein functions as a trypanolytic factor, but T. brucei rhodesiense and T.
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