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Heft Neal on Muck Rack

Heft Neal

As seen in: Cancer Research
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Articles

Sensitive MRD Detection from Lymphatic Fluid after Surgery in HPV-Associated Oropharyngeal Cancer

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By Lipid Research, Droplet Biosciences, Heft Neal
| Cancer Research Verified
Purpose: Our goal was to demonstrate that lymphatic drainage fluid (lymph) has improved sensitivity in quantifying postoperative minimal residual disease (MRD) in locally advanced human papillomavirus (HPV)-associated oropharyngeal squamous cell carcinoma (OPSCC) compared with plasma, and leverage this novel biofluid for patient risk stratification.
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Prognosis to Radiation Unlocked: How Hypoxia Methylome may hold the Key in HNSCC

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By Heft Neal, J. Chad
| Cancer Research Verified
Hypoxia in head and neck tumors has proven to be predictive of outcomes. Current hypoxia signatures have failed for patient treatment selection. In a recent study, the authors identified a hypoxia methylation signature as a more robust biomarker in HNSCC and shed light into the mechanism of hypoxia-mediated treatment resistance.
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