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Hege-Merete Krabseth on Muck Rack

Hege-Merete Krabseth

As seen in: Wiley Online Library, Clinical Therapeutics
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Articles

Effect of Bariatric Surgery on the Pharmacokinetics of Codeine, Oxycodone and Tramadol-A Case Series

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By Olav Spigset, Hege-Merete Krabseth, Magnus Strømmen, Arne Helland
| Wiley Online Library Verified
1 Introduction Obesity is a global health concern of considerable magnitude, highly associated with cardiovascular diseases, type 2 diabetes, some types of cancers and respiratory, digestive and musculoskeletal disorders [1]. According to the World Health Organization, 2.5 billion adults were overweight in 2022 and of these, 890 million had obesity [2]. The prevalence is clearly increasing, with a corresponding rise in the total obesity-related disease burden [1].
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Effect of bariatric surgery on the pharmacokinetics of drugs used for attention‐deficit hyperactivity disorder-A case series

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By Hege-Merete Krabseth, Magnus Strømmen, NTNU Norwegian, Arne Helland
| Wiley Online Library Verified
Plain English Summary After surgery for obesity the systemic exposure of drugs may be affected, which may lead to changes in the efficiency of medications. The aim of this study was to evaluate the effects of surgery on the pharmacokinetics of dexamphetamine, lisdexamphetamine, methylphenidate and atomoxetine. We obtained serum concentrations from eight patients before surgery and at different times after surgery.
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Effect on QTc interval by switching from methadone to equipotent R‐methadone dose in methadone maintenance treatment patients

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By Hege-Merete Krabseth, Stine Marie Havig, Riikka Mari Berg-Pedersen, Lill Dannevig Müller
| Wiley Online Library Verified
1 INTRODUCTION AND BACKGROUND Methadone is a synthetic opioid, used for managing pain and maintenance treatment in opioid dependence. The drug is a racemic mixture of R-(laevorotatory) and S-(dextrorotatory) stereoisomers.
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