Heiki Vija

Abstract Silver-containing nanomaterials are versatile antimicrobials for slowing down the rapid increase of nosocomial infections caused by antibiotic-resistant bacteria. However, silver can also promote resistance in bacteria to both silver itself and conventional antibiotics. Despite this, the topic is still poorly studied.

Open AccessArticle by *, , , and Laboratory of Environmental Toxicology, National Institute of Chemical Physics and Biophysics, Akadeemia Tee 23, 12618 Tallinn, Estonia * Author to whom correspondence should be addressed.

The novel set-up of our measurement system involving direct measurement of bacterial bioluminescence on solid surfaces was optimized to provide a reproducible test protocol. Due to the size of copper coupons (1 × 1 cm), 12-well plates were selected as a testing platform in this study. However, other plate types accommodating the surfaces of interest can also be selected.