Heilyn Joanna Nils

Ayuda Buscar en la ayuda Buscar en la ayuda Evaluación de la efectividad y seguridad de los glucocorticoides en el manejo del dolor postoperatorio en cirugía endodóntica periapical Autores: Heilyn Joanna Nils Directores de la Tesis: Javier Flores Fraile (dir.

1. Introduction Osteomyelitis is an infectious pathology of the bones. The term was coined by the French surgeon Auguste Nélaton in 1844 [1]. In 1852, Édouard-Pierre-Marie Chassaignac provided a detailed description of osteomyelitis, characterizing it as a pathology that originates from an inflammatory process within the bone tissue. By this time, the disease and its pathogenesis were already recognized, but Chassaignac’s work contributed to a more precise understanding of its underlying mechanisms.

1. Introduction Steroids are the most used medication, with high efficacy against inflammatory and immune diseases, pain, edema, and lockjaw [1]. Glucocorticoids are drugs derived from cholesterol (hence their name as steroidal drugs). They are synthesized by the adrenal cortex, along with other hormones, such as cortisol and aldosterone.