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Heng-Yue Peng on Muck Rack

Heng-Yue Peng

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AP-1-IL-1β signaling pathway on impulsive-like behavior and memory deficits in aged mice under tibial plateau fracture conditions

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By Lu-Ying Wang, Yu-Dong Shan, Lan-Xin Li, Xiao-Ming Li, Li-Min Zhang, Sheng-Jun Jiao, Heng-Yue Peng, Jia-Ling Hu, Jian-Yong Zhao, Wen-Tao Yu
| Nature Verified
Abstract Tibial fracture surgery has attracted significant interest as a notable trigger for PND. Under external stimuli such as anesthesia and surgery, the transcription factor AP-1 regulates the abnormal expression of glutamatergic neurons via interleukin-1β (IL-1β), a mechanism closely related to the pathophysiology of neurodegenerative diseases.
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