Manas K. Chattopadhyay‡1, Chithra N. Keembiyehetty§, Weiping Chen§ and Herbert Tabor‡ From the ‡Laboratory of Biochemistry and Genetics and the §Genomic Core Facility, NIDDK, National Institutes of Health, Bethesda, Maryland 20892 ↵1 To whom correspondence should be addressed: NIDDK, NIH, 8 Center Dr., Bldg. 8, Rm. 219, Bethesda, MD 20892-0830. Tel.: 301-496-1058; Fax: 301-402-0240; E-mail: manasc{at}intra.niddk.nih.gov. Background: Polyamines are ubiquitous compounds present in most organisms.