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Herreet Paul

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Articles

A murine model of cardiovascular-kidney-metabolic syndrome demonstrates compromised limb function in the ischemic hind limb

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By Vipul Chitalia, Saran Lotfollahzadeh, Herreet Paul, Joshua Bonefascio
| BioRxiv
Abstract Background: Cardiovascular-Kidney-metabolic (CKM) syndrome is a public health problem involving > 90% of the US and results in premature CVD at a relatively preserved GFR. The molecular mediators of CKM are poorly understood, partly due to the lack of a reliable animal model. We set out to generate an animal model with renal and metabolic dysfunctions, using PAD as a CKM manifestation.
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