Hetian Sun on Muck Rack

Hetian Sun

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Articles

β1,4-galactosyltransferase III drives retinoblastoma invasion via activation of integrin-FAK axis

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By Junjie Tang, Jinmiao Li, Meng Wang, Yaoming Liu, Zhihui Zhang, Yang Gao Verified, Shuxia Chen, Ping Zhang, Youjin Hu, Rong Lu, Hetian Sun, Siming Ai, Shicai Su
| Nature Verified
Abstract Retinoblastoma (RB) is the most common primary intraocular malignancy in children, and its extraocular extension is closely linked to poor prognosis. However, the molecular drivers underlying local invasion remain incompletely defined. Here, we identify β‑1,4‑galactosyltransferase III (B4GALT3) as a glycosyltransferase selectively upregulated in highly proliferative MKI67⁺ RB subpopulations.
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