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Effectiveness and safety of exercise therapy in patients with myalgic encephalomyelitis/chronic fatigue syndrome: a meta-analysis
1 Introduction Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a chronic disease primarily characterized by unexplained, persistent fatigue. It is often accompanied by multisystem symptoms, such as unrefreshing sleep, cognitive dysfunction, orthostatic intolerance, and pain (1). Since the outbreak of COVID-19 in 2019, ME/CFS has been recognized as one of the most common clinical subtypes of long COVID.
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