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Hindra Hindra on Muck Rack

Hindra Hindra

As seen in: BioRxiv
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Articles

A complex regulatory network governs the production of an antibiotic with unusual cell-density-dependence

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By Marie A. Elliot, Hindra Hindra
| BioRxiv
Abstract Streptomyces bacteria are renowned both for their antibiotic production capabilities, and for their cryptic metabolic potential. Here, we leveraged the activity of an Lsr2 knockdown construct to enhance antibiotic production in the wild Streptomyces isolate WAC07094. We determined the new activity stemmed from increased levels of the angucycline-like family member saquayamycin.
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