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LUZP1 regulates the assembly of stress fibers by promoting maturation of contractile actomyosin bundles
Abstract Contractile actomyosin bundles play crucial roles in various physiological processes. The intricate assembly of actomyosin bundles involves the precise alignment and fusion of myosin II filaments, yet the underlying mechanisms and factors involved in these processes remain incompletely understood. Our study reveals that LUZP1 plays a central role in orchestrating the formation of thick actomyosin bundles, which is essential for cell contractility and migration.
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