Hong Mu-Mosley

Results Clinical characterization of patients and study design A total of 162 patients were included in the study. Figure 1 outlines the overall experimental strategy and patient cohorts included in each analysis, including cytokines/chemokines (n=146), ANA (n=65), CyTOF (n=55), and scRNA-seq (n=36). The overall numbers and selection of cases for each assay reflect cost/resources, specimen availability, and an effort to maximize the overlap of cases across assays.

Abstract Introduction: Racial and ethnic disparities in the presentation and outcomes of lung cancer are widely known. To evaluate potential factors contributing to these observations, we measured systemic immune parameters in Black and White patients with lung cancer. Methods: Patients scheduled to receive cancer immunotherapy were enrolled in a multi-institutional prospective biospecimen collection registry. Clinical and demographic information were obtained from electronic medical records.