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As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.Articles
The role of bile acid receptors in cholestatic liver disease: pathophysiological insights and therapeutic advances
ABSTRACT Introduction Cholestatic liver disease (CLD) is a group of hepatobiliary disorders characterized by impaired bile flow, leading to the accumulation of toxic bile acids (BAs) and progressive liver injury. The available pharmacotherapies are limited and often inadequate. Areas covered This review explores the therapeutic potential of BA-activated receptors, encompassing nuclear receptors and membrane-bound G protein-coupled receptors, in the context of CLD.
Revealing the pathogenesis of autoimmune hepatitis and research progress in drug discovery from hepatic immune cells and intercellular communication signaling mechanisms
Abstract Autoimmune hepatitis (AIH) is an immune-mediated chronic liver disease with an increasing incidence. The complex pathogenesis of AIH poses significant challenges for clinical treatment.
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