Hope Adamson

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Monoclonal antibody (mAb) drugs have been a resounding clinical and commercial success, applied across a range of therapeutic areas with a particularly significant impact in the treatment of cancer, autoimmune and inflammatory diseases [1–4]. High-interaction surface area binding gives mAbs greater specificity and so lower off-target, toxic effects compared with small-molecule drugs [3].

Abstract Plant viruses can cause devastating losses to agriculture and are therefore a major threat to food security. The rapid identification of virally-infected crops allowing containment is essential to limit such threats, but plant viral diseases can be extremely challenging to diagnose. An ideal method for plant virus diagnosis would be a device which can be implemented easily in the field. Such devices require a binding reagent that is specific for the virus of interest.