Hosam Shalaby

This is an early access version, the complete PDF, HTML, and XML versions will be available soon. Open AccessArticle by 1,*, 1, 2, 1, 1, 1 and 1,* 1 Department of Urology, School of Medicine, Tulane University, New Orleans, LA 70112, USA 2 School of Medicine, Tulane University, New Orleans, LA 70112, USA * Authors to whom correspondence should be addressed.

Abstract : Simple Summary As a solid tumor, melanoma is not only a tumor mass of monolithic tumor cells, but it also contains supporting stroma, extracellular matrix (ECM), and soluble molecules forming the widely recognized tumor microenvironment. The main components of the tumor microenvironment include stromal cells (endothelial cells, fibroblasts, mesenchymal stem cells, and immune cells), ECM, and soluble molecules (chemokines, cytokines, growth factors, and extracellular vesicles).

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