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Houyan Zhang on Muck Rack

Houyan Zhang

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Articles

A Hippo-YAP pathway activity-guided multimodal framework highlights NDRG1-associated tumor microenvironmental features in hepatocellular carcinoma

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By Dongjie Wu, Bohao Huang, YuDan Fu, Zhiya Yang, Yanbo Li, Wenliang Lv, Houyan Zhang, Erjun Gao
| Nature Verified
Abstract Hepatocellular carcinoma (HCC) is characterized by marked molecular and histopathological heterogeneity, which limits the performance of conventional clinicopathological risk stratification systems. Hippo-YAP signaling is closely involved in HCC progression and tumor microenvironment regulation. However, how Hippo-YAP pathway activity is reflected in histopathological phenotypes and intercellular communication patterns remains insufficiently understood.
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