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Hsing‐Chuan Tsai on Muck Rack

Hsing‐Chuan Tsai

As seen in: Color Research & Application
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Articles

Cholera toxin enhances interleukin‐17A production in both CD4+ and CD8+ cells via a cAMP/protein kinase A‐mediated interleukin‐17A promoter activation - Tsai - - Immunology - Wiley Online Library

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By Sharlene Velichko, Shanshan Lee, Reen Wu, Hsing‐Chuan Tsai
| Color Research & Application Verified
Cholera toxin (CT) is a bacterial component that increases intracellular cAMP levels in host cells and suppresses T‐cell activation. Recently, CT was reported to induce T helper type 17‐skewing dendritic cells and activate interleukin‐17A (IL‐17A) production in CD4+ T cells through a cAMP‐dependent pathway. However, the underlying mechanism by which cAMP regulates IL‐17A production in T cells is not completely defined.
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