Huan Huang on Muck Rack

Huan Huang

As seen in: Nature, Wiley Online Library, Cambridge University Press & Assessment, PLOS, PLOS ONE, Frontiers, Frontiers in Public Health, MDPI, Taylor & Francis Online, Genome Biology and
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Articles

Metabolic stress exacerbates Parkinson’s disease pathology through mitochondrial dysfunction and ferroptosis

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By Yanyan Zheng, Huan Huang, Sisi Wang, Wenyuan Wang, Wenjia Wang, Chen Gao, Quan Zhang, qiang li, Zhongpeng Dai, Liuxi Chu, Feiyu Ding, Minyan Ye
| Nature
Abstract Epidemiological studies have linked type 2 diabetes to Parkinson’s disease (PD), but causality and mechanisms remain unclear. Here, using Mendelian randomization, we identify genetically elevated 2‑hour post‑load glucose as a causal risk factor for PD. To investigate the underlying biology, we developed a mouse model combining glucose intolerance with MPTP‑induced dopaminergic injury.
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Global epidemiological trends, distribution of NTDs and malaria, and disease burden projections for the next 15 years

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By Huan Huang, Yang Gao , Huajing Zhu, Yameng Xu, Fanjin Meng, Xinyan Chen, Weibo Ma, Yuanyuan Li, Weilong Tan, Minli Li, Gengting Du, Jiaojiao Qian
| Frontiers in Public Health
Abstract Background: This study investigates global and regional trends in the burden of malaria and neglected tropical diseases (NTDs) from 1990 to 2021, focusing on their changing patterns and influencing factors. Using data from the Global Burden of Disease study 2021 (GBD study 2021), we analyzed the incidence, prevalence, mortality, disability-adjusted life years (DALYs), and age-standardized rates (ASRs) of malaria and NTDs at both regional and global levels.
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Central city construction and urban land green utilization efficiency: evidence from Chinese urban agglomerations

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By Yi Xiao, Haonan Yang, Huan Huang, Liang Chen, Ming Chang, Qingshen Kong
| Nature
Abstract Central city construction (CCC) functions as an important policy instrument for facilitating China’s green transformation, while urban agglomerations serve as the primary spatial carriers of this process. In the context of low land utilization efficiency and environmental pressure, this study examines how CCC influences urban land green utilization efficiency (ULGUE) within urban agglomerations (UAs).
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