Huangchao Jia

Abstract Background: Sanyin decoction (SYD) is an improved formulation based on Xiaoyinsan, commonly used as an adjunct treatment for psoriasis; however, its molecular mechanisms remain unclear. Methods: A psoriasis-like mouse model was established using imiquimod induction. Mice were treated with SYD via gavage, and their health status was assessed based on skin histopathology, PASI scores, and ear thickness measurements.

1 Introduction Acquired immune deficiency syndrome (AIDS) is induced by human immunodeficiency virus (HIV) and continues to be a significant global public health problem1 (1, 2). Since the beginning of the AIDS epidemic, a total of 40.1 million people have died of AIDS-related illnesses. In 2021, there were an estimated 38.4 million people living with HIV (PLHIV) globally, 1.5 million people newly infected with HIV, and 650 thousand people who died of AIDS-related illness (3).

Back to Journals » Clinical, Cosmetic and Investigational Dermatology » Volume 19 Authors Niu W , Li J, Jia H, Wang L, Xu M, Liu X Received 20 September 2025 Accepted for publication 17 January 2026 Published 29 January 2026 Volume 2026:19 Pages 1—17 DOI https://doi.org/10.2147/CCID.S566075 Checked for plagiarism Yes Review by Single anonymous peer review Peer reviewer comments 2 Editor who approved publication: Prof.