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Huanxin Yin

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Articles

DDX3x Regulates NINJ1 Transcription via Histone Lactylation in Sepsis Associated-Acute Kidney Injury

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By Hongyu Liang, Jihong Jiang, Huanxin Yin
| Wiley Online Library Verified
1 Introduction Sepsis is defined as a life-threatening organ dysfunction caused by a dysregulated host response to infection, with approximately 90% of ICU patients exhibiting varying degrees of sepsis [1]. Acute kidney injury (AKI) frequently complicates critical illness. The diagnostic criteria for AKI primarily rely on various serum markers of renal injury (e.g., an increase in serum creatinine of ≥50% within 7 days) [2].
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