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Huanying Shi on Muck Rack

Huanying Shi

As seen in: Nature, Wiley Online Library, Frontiers in Immunology
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Articles

IL1B-centered immune dysregulation involving IL7R, CCR7, ITGB2 and IRF1 across insomnia and inflammatory bowel disease

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By Han Guo, Xudong Xu, Huanying Shi, Meng Cui, Min Zhang, Hongdan Wang, Yunxuan Zhang, Haifeng Zhou, Xu Sun, Xiaoyan Liu
| Frontiers in Immunology
Abstract Background: Insomnia is a prevalent sleep disorder that strongly affects one’s quality of life and physical well-being. Inflammatory bowel disease (IBD) is a chronic inflammatory condition of the intestines, and a majority of IBD patients suffer from comorbid insomnia. However, the shared molecular features linking insomnia and IBD remain poorly characterized.
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Metabolism score and machine learning models for the prediction of esophageal squamous cell carcinoma progression

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By Lu Chen, Wenxin Zhang, Huanying Shi, Yongjun Zhu
| Wiley Online Library Verified
1 INTRODUCTION Esophageal cancer is one of the most prevalent malignancies worldwide, ranking seventh in terms of incidence and being the sixth leading cause of cancer-related deaths.1 Esophageal cancer can be classified into two distinct diseases based on its epidemiology and pathology: esophageal squamous cell carcinoma (ESCC) and esophageal adenocarcinoma.2 Global statistics from the WHO indicate that in 2018, there were approximately 572,000 newly diagnosed cases of esophageal cancer,...
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Nur77-IRF1 axis inhibits esophageal squamous cell carcinoma growth and improves anti-PD-1 treatment efficacy - Cell Death Discovery

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By Haifei Chen, Yongjun Zhu, Huanying Shi
| Nature Verified
Abstract The nuclear receptor Nur77 plays paradoxical roles in numerous cancers. However, whether Nur77 inhibits esophageal squamous cell carcinoma (ESCC) growth and affects immunological responses against ESCC has not been determined. The functional role of Nur77 in ESCC was investigated in this study using human ESCC cell lines, quantitative real-time polymerase chain reaction (PCR), cell proliferation and colony formation assays, flow cytometry analysis, western blotting and animal models.
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