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Huaying Pei on Muck Rack

Huaying Pei

As seen in: Frontiers in Medicine
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Articles

Low-dose daratumumab and bortezomib for the treatment of proliferative glomerulonephritis with monoclonal immunoglobulin deposits: a case report

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By Jiaomei Zhu, Limin Zhang, Huibo Zhao, Li Tian, Shaomei Li, Lingling Xing, Huaying Pei
| Frontiers in Medicine
Abstract Background: Proliferative glomerulonephritis with monoclonal immunoglobulin deposits (PGNMID) is an exceptionally rare glomerular disease, accounting for only 0.17–3.7% of all renal biopsies, and no consensus–based treatment algo-rithm has been established. Although daratumumab, a humanized anti-CD38 monoclonal antibody, has shown promising efficacy in PGNMID, the existing evidence is limited to small case series using standard-dose regimens (16 mg/kg).
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