Huazhuo Wu on Muck Rack

Huazhuo Wu

As seen in: Frontiers in Immunology
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Articles

Melatonin alleviates airway inflammation and anxiety-depression in asthma via gut microbiota–SCFA axis-mediated inhibition of microglial activation

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By Jiahao Lai, YUE WANG, Qinglin Deng, Jinyu Liao, Chaoqun Sun, Yan Geng, Dan Huang, Xuanna Zhao, Dong Wu, Liwan Zeng, Youping Qiao, Huazhuo Wu
| Frontiers in Immunology
Abstract Background: Asthma frequently co-occurs with anxiety and depression, yet the mechanisms underlying this lung-brain comorbidity remain elusive. The gut-lung-brain axis has emerged as a potential key mediator. Methods: Using an ovalbumin (OVA)-induced murine asthma model, we administered melatonin or sodium butyrate via drinking water.
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