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Articles

Cell-Specific Single Viral Vector CRISPR/Cas9 Editing and Genetically Encoded Tool Delivery in the Central and Peripheral Nervous Systems

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By Bygrave AM, Huganir RL, Roth RH, Johnson RC
| eneuro.org
CRISPR/Cas9 gene editing imaging optogenetics photometry tool Significance Statement Our CRISPR/Cas9 approach is the first to use a single vector to both knockdown genes of interest and express tools to monitor, map, and manipulate neurons. We demonstrate its utility in the central nervous system and describe the first systemic CRISPR/Cas9 gene editing with coexpressed reporters in the peripheral nervous system.
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ICA69 regulates activity-dependent synaptic strengthening and learning and memory

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By Chiu SL, Chen CM, Huganir RL
| ncbi.nlm.nih.gov
Save citation to file Format: Add to My Bibliography Your saved search Name of saved search: Search terms: Frequency: Which day? Which day? Report format: Send at most: Send even when there aren't any new results Optional text in email: Create a file for external citation management software
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