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Hugo Lewi Hammer on Muck Rack

Hugo Lewi Hammer

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Articles

Serum metabolomic signal in dry eye disease in a family aware twin cohort

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By Leif Hynnekleiv, Pirro G. Hysi, Chris Hammond, Michael A. Riegler, Jelle Vehof, Hugo Lewi Hammer
| Nature Verified
Abstract Dry eye disease is common and heterogeneous, but whether retrospective blood metabolite profiles capture dry-eye signal remains unclear. We performed a retrospective machine-learning analysis of untargeted serum metabolomics in TwinsUK, using approximately 4,200 serum samples from approximately 1,400 participants and two questionnaire-derived outcomes: a broad Women’s Health Study dry-eye definition and a more specific highly symptomatic phenotype.
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