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Hui-ying Guan on Muck Rack

Hui-ying Guan

As seen in: Frontiers
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Articles

Different stages of Alzheimer’s disease with periodontitis: clinical features and potential mechanisms involving gingipains, neuropathological biomarkers and neurological damage

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By Jing-Hui Li, Peng Guo, Jing Qi, Ming-Yue He, Ya-Nan Zhang, Yue Huang, Wei-Jia Zhang, Zi-Jing Zheng, Hao Yue, Zhan Liu, fan zhang, Yao Meng, Teng-hong Lian, Dong-mei Luo, Gai-fen Liu, Hui-ying Guan
| Frontiers
Abstract Background: Alzheimer’s disease (AD) and periodontitis are common in older adults aged over 65 years. However, the clinical features and mechanisms at the stages of mild cognitive impairment and dementia due to AD (AD-MCI and AD-D) remain unknown. Methods: In 110 patients with AD-MCI and AD-D, oral hygiene, periodontitis status, clinical symptoms and the levels of gingipain, neuropathological biomarkers and neurological damage indicators in cerebrospinal fluid were evaluated.
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