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Huiying Mu

As seen in: Royal Society of Chemistry
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Articles

Light-controllable cell-membrane disturbance for intracellular delivery

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By Wenting Huo, Koji Miki, Huiying Mu, Takashi Osawa
| Royal Society of Chemistry Verified
Light-controllable cell-membrane disturbance for intracellular delivery Highly polar and charged molecules, such as oligonucleotides, face significant barriers in crossing the cell membrane to access the cytoplasm. To address this problem, we developed a light-triggered twistable tetraphenylethene (TPE) derivative, TPE-C-N, to facilitate the intracellular delivery of charged molecules through an endocytosis-independent pathway.
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A reductively convertible nickel phthalocyanine precursor as a biological thiol-responsive turn-on photoacoustic contrast agent

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By Kohei Nogita, Koji Miki, Huiying Mu, Takaya Sugahara
| Royal Society of Chemistry Verified
A reductively convertible nickel phthalocyanine precursor as a biological thiol-responsive turn-on photoacoustic contrast agent† A nickel phthalocyanine precursor bearing poly(ethylene glycol) as a turn-on contrast agent for photoacoustic imaging was prepared. The water-soluble polymeric chains were smoothly eliminated through thiol-mediated reductive aromatization in cancer cells, enabling the detection of endogenous biological thiols in vitro and in vivo.
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Substituted meso-Vinyl-BODIPY as Thiol-Selective Fluorogenic Probes for Sensing Unfolded Proteins in the Endoplasmic Reticulum

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By Koji Miki, Takuya Kubo, Huiying Mu, Koji Otsuka
| Royal Society of Chemistry Verified
Substituted meso-Vinyl-BODIPY as Thiol-Selective Fluorogenic Probes for Sensing Unfolded Proteins in the Endoplasmic Reticulum You have access to this article Please wait while we load your content... Something went wrong. Try again?
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