Hung Long Ngo on Muck Rack

Hung Long Ngo

As seen in: Wiley Online Library
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Articles

Checkpoint kinase 1 inhibitor + low‐dose hydroxyurea efficiently kills BRAF inhibitor‐ and immune checkpoint inhibitor‐resistant melanomas

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By Zhen Zeng, Martina Proctor, Helen Rizos, Hung Long Ngo
| Wiley Online Library
The lack of effective alternative treatments for patients who develop resistance to targeted and/or immunotherapies is a significant problem for a large proportion of melanoma patients. CHK1i + LDHU is an effective treatment in a high proportion of melanomas and retains this efficacy in current treatment-resistant tumours. This suggests that CHK1i + LDHU could be an effective alternative therapy in otherwise treatment-resistant melanoma patients.
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