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Huoying Chen on Muck Rack

Huoying Chen

As seen in: Frontiers in Immunology
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Articles

Frontiers | CD48, CD69, and TIGIT as diagnostic biomarkers for primary Sjögren’s syndrome: an integrated machine learning and multi-disease discrimination validation study

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By Linlin Xu, Pingping Jiang, Yang Xiao, Hongling Wang, Hongbo Liu, Huoying Chen
| Frontiers in Immunology
1 Introduction Primary Sjögren’s syndrome (pSS) is a systemic autoimmune disorder (1) characterized primarily by sicca symptoms (xerostomia and xerophthalmia) (2, 3). Progressive involvement of extraglandular organs (e.g., renal, pulmonary, gastrointestinal, and neurological systems) frequently occurs (4), resulting in multisystem damage that substantially impairs quality of life (5–8). The diagnosis of pSS remains challenging due to its insidious onset and non-specific early manifestations.
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