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Etiopathogenesis, Prevention, and Treatment of Thromboembolism in Inflammatory Bowel Disease
Introduction The close relationship between inflammation and thrombosis, as observed in many other inflammatory diseases, affects the progression and severity of inflammatory bowel disease (IBD), which is composed of 2 main types, Crohn disease (CD) and ulcerative colitis (UC).1 It is known that the risks of arterial and venous thrombosis have increased in IBD since they were first reported in 1936 by Bargen and Barker.2 Although nearly 80 years have passed, the interaction between IBD and...
Etiopathogenesis, Prevention, and Treatment of Thromboembolism in Inflammatory Bowel Disease
The close relationship between inflammation and thrombosis affects the progression and severity of inflammatory bowel disease (IBD). The prevalence of venous thromboembolism (VTE) varies between 1% and 7% among patients with IBD. The VTE risk in patients with IBD is at least 3 times higher than that in the normal general population. The absolute risk is very high during hospitalization, active disease, and surgery. The IBD-related VTE occurs at younger ages and recurs more frequently.
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