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Hwee Hui Lau on Muck Rack

Hwee Hui Lau

As seen in: Nature, Stem Cell Reports
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Articles

STARD10 regulates human pancreatic β cell differentiation and triglyceride metabolism

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By Wei Xuan Tan, Nur Shabrina Amirruddin, Ming Hu, Sneha Muralidharan, Peter I Benke, Federico Torta, Shawn Hoon, Hwee Hui Lau, Natasha Ng, Guy A. Rutter
| Stem Cell Reports Verified
ReportOnline now102815Open access 1Stem Cells and Diabetes Laboratory, Institute of Molecular and Cell Biology, A∗STAR, Singapore 138673, Singapore 2Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119228, Singapore 3Precision Medicine Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119228, Singapore 4Section of Cell Biology and Functional Genomics, Imperial College London,...
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PAX4 loss of function increases diabetes risk by altering human pancreatic endocrine cell development - Nature Communications

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By Yunkyeong Lee, Han Sun, Daphne Su-Lyn Gardner, E. Shyong Tai, Anna L Gloyn, Hwee Hui Lau, Marta Perez-Alcantara
| Nature Verified
Abstract The coding variant (p.Arg192His) in the transcription factor PAX4 is associated with an altered risk for type 2 diabetes (T2D) in East Asian populations. In mice, Pax4 is essential for beta cell formation but its role on human beta cell development and/or function is unknown.
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