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Hyeonki Kim on Muck Rack

Hyeonki Kim

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Articles

Oxygen-dependent subcellular redistribution of PHD3 links the hypoxic microenvironment to mitochondrial metabolic reprogramming in ccRCC

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By Soyeon Lim, Changjun Lee, Hani Kim, Hojun Lee, Kimyeong Kim, Mahesh Teli, Kyeong Beom Jo, Jacob Wright, Jee Park, Myung Eun Lee, Minsun Jung, Minsoo Noh, Dae-Kyum Kim, Mi-Hyun Kim, Dong Wook Choi, Tae Su Choi, Hunsang Lee, Haejin Yoon, Jaelim Sim, Hyeonki Kim
| Nature Verified
Abstract Clear cell renal cell carcinoma (ccRCC) is characterized by profound metabolic dysregulation, with both prolyl hydroxylase domain protein 3 (PHD3) and pyruvate carboxylase (PC) independently implicated in disease progression. Although each influences patient outcomes, a direct mechanistic interplay between these two regulators has remained elusive.
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